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GenieFluor Violet 450 Anti-Mouse CD161/NK1.1 Antibody [PK136] (AGEL2941)

SKU:
AGEL2941
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Mouse
Isotype:
Mouse IgG2a, κ
Clone:
PK136
Conjugation:
AFViolet 450
$239 - $467

Description

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GenieFluor Violet 450 Anti-Mouse CD161/NK1.1 Antibody [PK136]

The GenieFluor Violet 450 Anti-Mouse CD161 (NK1.1) Antibody (PK136) is a powerful tool for researchers studying immune responses in mice. This monoclonal antibody specifically targets CD161 (NK1.1), a marker found on natural killer cells and other immune cell subsets. By binding to CD161, the PK136 antibody allows for precise detection and analysis of these crucial cell populations in various experimental settings.Natural killer cells are essential components of the immune system, playing a key role in the recognition and elimination of infected or abnormal cells. CD161 is a marker that helps identify and characterize these specialized immune cells, providing valuable insights into their function and behavior. The PK136 antibody, optimized for use in mouse samples, enables researchers to explore the role of CD161-positive cells in immune responses, inflammation, and disease progression.

Whether investigating immune surveillance, infection responses, or immunotherapy outcomes, the GenieFluor Violet 450 Anti-Mouse CD161 (NK1.1) Antibody (PK136) offers reliable and accurate detection capabilities. Its compatibility with flow cytometry and other analytical techniques makes it a versatile choice for studies focusing on natural killer cells and immune cell subsets in murine models. Unlock the potential of your research with this high-quality antibody designed for precise targeting and analysis of CD161-expressing cells in mouse systems.

Product Title:GenieFluor Violet 450 Anti-Mouse CD161/NK1.1 Antibody [PK136]
SKU:AGEL2941
Size:25µg, 100µg
Clone No:PK136
Synonyms:Killer cell lectin-like receptor subfamily B member 1C;Klrb1c;CD161 antigen-like family member C;Ly-55c;CD161/NK1.1;NKR-P1.9;NKR-P1C;NKR-P1 40;CD161c;
Host Species:Mouse
Reactivity:Mouse
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:Genie Fluor Violet 450 Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P27814 P27812 Q99JB4
Gene ID:17059
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

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