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GenieFluor Violet 450 Anti-Mouse CD161/NK1.1 Antibody [PK136] (AGEL2940)

SKU:
AGEL2940
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Mouse
Isotype:
Mouse IgG2a, κ
Clone:
PK136
Conjugation:
AFViolet 450
€149
Frequently bought together:

Description

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GenieFluor Violet 450 Anti-Mouse CD161/NK1.1 Antibody [PK136]

The GenieFluor Violet 450 Anti-Mouse CD161/NK1.1 Antibody (PK136) is a cutting-edge tool designed for researchers working in the field of immunology. This antibody, known as AGEL2940, is specifically targeted towards CD161/NK1.1, cell surface markers associated with natural killer (NK) cells and other immune cell subsets. Through its exceptional specificity and sensitivity, this antibody allows for precise detection and analysis of CD161/NK1.1 in various mouse cell types.CD161/NK1.1 is a crucial receptor involved in the activation and function of NK cells, a key player in the innate immune system's defense against infections and tumors. By targeting this receptor with the GenieFluor Violet 450 Anti-Mouse CD161/NK1.

1 Antibody, researchers can gain valuable insights into the role of NK cells in immune responses, inflammation, and disease progression. This antibody is an indispensable tool for studies focusing on NK cell biology, immunotherapy, infectious diseases, and autoimmune conditions.With its high reactivity and reliability in experimental applications such as flow cytometry and immunofluorescence, the GenieFluor Violet 450 Anti-Mouse CD161/NK1.1 Antibody (PK136) offers a versatile and powerful solution for researchers striving to unravel the complexities of the immune system and develop novel therapeutic strategies.

Product Title:GenieFluor Violet 450 Anti-Mouse CD161/NK1.1 Antibody [PK136]
SKU:AGEL2940
Size:50 Tests, 100 Tests, 200 Tests
Clone No:PK136
Synonyms:Killer cell lectin-like receptor subfamily B member 1C;Klrb1c;CD161 antigen-like family member C;Ly-55c;CD161/NK1.1;NKR-P1.9;NKR-P1C;NKR-P1 40;CD161c;
Host Species:Mouse
Reactivity:Mouse
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:Genie Fluor Violet 450 Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P27814 P27812 Q99JB4
Gene ID:17059
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

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