The GenieFluor Violet 450 Anti-Mouse CD16/32 Antibody (2.4G2) from Assay Genie is a high-quality reagent designed for research involving mouse CD16/32, also known as Fc gamma receptor III and II. This antibody is monoclonal and specifically recognizes CD16/32 antigens in mouse samples. CD16/32 is a cell surface receptor expressed on immune cells, such as macrophages and natural killer cells, and plays a crucial role in mediating immune responses. The GenieFluor Violet 450 Anti-Mouse CD16/32 Antibody (2.4G2) is validated for use in various experimental applications, including flow cytometry and immunofluorescence, enabling precise detection and analysis of CD16/32-expressing cells.
By targeting CD16/32, researchers can gain insights into immune cell activation, function, and signaling pathways, advancing studies in immunology, inflammation, infectious diseases, and cancer research. The GenieFluor Violet 450 Anti-Mouse CD16/32 Antibody (2.4G2) is a valuable tool for investigators seeking to explore the role of CD16/32 in immune regulation and disease pathogenesis.
CD16a/b;CD32;CD32A/B;Fc fragment of IgG low affinity IIa/b receptor;Fc fragment of IgG low affinity IIIa/b receptor;Fc fragment of IgG low affinity IIIb receptor;Fc gamma receptor III A/B;FCG2A;FcGR;FCGR2A/BFCGR3;FCGR3A/B;Fc gamma RIIa/b ;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
Genie Fluor Violet 450 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
Genie FluorViolet 450
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P08508 P08101
Gene ID:
14130,14131
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.