The GenieFluorâ„¢ Violet 450 Anti-Mouse CD14 Antibody (SA14-2) is a powerful tool for researchers studying mouse CD14, a key cell surface receptor involved in the recognition of bacterial lipopolysaccharide and other microbial products. This antibody is specifically designed for flow cytometry applications and is highly reactive with mouse samples.CD14 is a crucial component of the innate immune system, playing a vital role in the detection and response to bacterial infections. By targeting CD14 with the GenieFluorâ„¢ Violet 450 Anti-Mouse CD14 Antibody, researchers can accurately identify and analyze CD14-expressing cells in various tissues and cell types.
This antibody is ideal for studies focusing on immune responses, inflammation, infection, and immune cell profiling in mouse models. With its high specificity and sensitivity, the GenieFluorâ„¢ Violet 450 Anti-Mouse CD14 Antibody (SA14-2) provides valuable insights into the functions and interactions of CD14, contributing to advancements in immunology and infectious disease research.
CD 14;Myeloid cell-specific leucine-rich glycoprotein;Monocyte differentiation antigen CD14;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
Genie Fluor Violet 450 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Genie FluorViolet 450
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P10810
Gene ID:
12475
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed on macrophages, dendritic cells, Kupffer cells, hepatocytes, and granulocytes. As a high-affinity receptor for LPS-LBP (LPS-binding protein) complex, CD14, in association with Toll-like Receptor 4 (TLR4) or 2 (TLR2), is involved in the clearance of gram-negative pathogens.