The GenieFluor Violet 450 Anti-Mouse CD11c Antibody (N418) is a cutting-edge tool designed for researchers studying immune cell biology, particularly dendritic cells. This antibody, meticulously produced and validated by Assay Genie, specifically targets the CD11c protein expressed on the surface of mouse dendritic cells. Its high affinity and specificity make it a superior choice for flow cytometry applications, allowing for precise identification and analysis of CD11c-positive cells.Dendritic cells, as key players in the immune system, are crucial for initiating and regulating immune responses. The CD11c protein, also known as integrin alpha X, is a well-established marker for dendritic cells, playing essential roles in antigen presentation and immune activation.
By utilizing the GenieFluor Violet 450 Anti-Mouse CD11c Antibody (N418), researchers can delve deeper into the functions and behaviors of dendritic cells in various physiological and pathological conditions.With its exceptional performance and reliability, this antibody is a valuable tool for advancing research in immunology, vaccine development, and autoimmune disease studies. By enabling accurate analysis and characterization of CD11c-expressing dendritic cells, the GenieFluor Violet 450 Anti-Mouse CD11c Antibody (N418) empowers scientists to unravel the complexities of the immune system and pave the way for innovative therapeutic strategies.
Integrin alpha-X;Itgax;CD11 antigen-like family member C;Leukocyte adhesion receptor p150+95;CD11c;
Host Species:
Armenian Hamster
Reactivity:
Mouse
Application:
FCM
Isotype:
Armenian Hamster IgG
Isotype Control:
Genie Fluor Violet 450 Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
Genie FluorViolet 450
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q9QXH4
Gene ID:
16411
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54.