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GenieFluor Violet 450 Anti-Mouse CD11c Antibody [N418] (AGEL3018)

SKU:
AGEL3018
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Armenian Hamster
Isotype:
Armenian Hamster IgG
Clone:
N418
Conjugation:
AFViolet 450
$251 - $611
Frequently bought together:

Description

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GenieFluor Violet 450 Anti-Mouse CD11c Antibody [N418]

The GenieFluor Violet 450 Anti-Mouse CD11c Antibody (N418) is a powerful tool designed for researchers studying immune cells expressing CD11c, a surface marker commonly found on dendritic cells. This antibody, specifically engineered for use in mouse samples, is derived from a hybridoma cell line and has been extensively validated for flow cytometry applications.CD11c is a key integrin involved in cell adhesion and immune cell interactions, particularly in antigen presentation and T cell activation processes. Its expression on dendritic cells serves as a valuable indicator for immune system activation and maturation.

The GenieFluor Violet 450 Anti-Mouse CD11c Antibody (N418) binds specifically to CD11c molecules, enabling precise detection and analysis of dendritic cells in various experimental settings.By targeting CD11c, researchers can delve into the functions and responses of dendritic cells in immune processes, such as antigen presentation and immune regulation. This antibody's reliability and specificity make it an indispensable tool for immunologists and researchers exploring the intricacies of immune cell biology and inflammatory responses in preclinical and basic research studies.

Product Title:GenieFluor Violet 450 Anti-Mouse CD11c Antibody [N418]
SKU:AGEL3018
Size:25µg, 100µg
Clone No:N418
Synonyms:Integrin alpha-X;Itgax;CD11 antigen-like family member C;Leukocyte adhesion receptor p150+95;CD11c;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:Genie Fluor Violet 450 Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q9QXH4
Gene ID:16411
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54.

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