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GenieFluor Violet 450 Anti-Mouse CD107a Antibody [1D4B] (AGEL3296)

SKU:
AGEL3296
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
ICFCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, k
Clone:
1D4B
Conjugation:
AFViolet 450
€279 - €639
Frequently bought together:

Description

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GenieFluor Violet 450 Anti-Mouse CD107a Antibody [1D4B]

The GenieFluor Violet 450 Anti-Mouse CD107a Antibody (1D4B) from Assay Genie is a cutting-edge tool designed for precise and reliable detection of CD107a, a crucial marker for the study of immune cell degranulation processes. This antibody is specifically developed for use in mouse samples, offering exceptional sensitivity and specificity in flow cytometry and immunofluorescence applications. By targeting the CD107a protein, researchers can accurately track and analyze the degranulation activity of immune cells in various experimental settings.CD107a, also known as lysosome-associated membrane glycoprotein 1 (LAMP-1), serves as a vital indicator of cytotoxic activity in immune cells, particularly in the context of cytotoxic T lymphocytes and natural killer cells.

Monitoring CD107a expression provides valuable insights into the functionality of these immune effectors, shedding light on mechanisms of cellular immunity and immune response regulation. The GenieFluor Violet 450 Anti-Mouse CD107a Antibody (1D4B) is a powerful tool for investigating immune cell function and exploring the intricate dynamics of cell-mediated immune responses.By utilizing this advanced antibody in your research, you can delve deeper into the role of CD107a in immune surveillance, infectious diseases, cancer immunology, and autoimmune disorders. Unleash the potential of your studies with the precision and reliability offered by the GenieFluor Violet 450 Anti-Mouse CD107a Antibody (1D4B) from Assay Genie.

Product Title:GenieFluor Violet 450 Anti-Mouse CD107a Antibody [1D4B]
SKU:AGEL3296
Size:50 Tests, 100 Tests, 200 Tests
Clone No:1D4B
Synonyms:LAMP-1;Lysosome-associated membrane glycoprotein 1; lysosomal membrane glycoprotein 1; CD107 antigen-like family member A; lysosome-associated membrane protein 1;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor Violet 450 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P11438
Gene ID:16783
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:The 1D4B antibody recognizes CD107a which is also known as, Lysosome-Associated Membrane Protein 1 (LAMP-1). CD107a is one of the two major glycoproteins in lysosome membranes that provide useful markers to distinguish lysosomes from other organelles. CD107a may play a role in the lysosomal degradation of certain molecules. Mouse CD107a is a type I transmembrane glycoprotein. It consists of a 40-kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140 kDa. It is principally expressed in epithelial cells and macrophages in a variety of organs. Following activation, CD107a is relocated to the surface of some lymphocytes, macrophages, epithelial cells, endothelial cells, platelets, and tumor cells. Cell-surface CD107a may participate in intercellular adhesion and adhesion to the extracellular matrix. Cell surface CD107a expression can serve as a useful marker for cytotoxic NK and CD8+ T cells, as well as, some malignant tumor cells.

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