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GenieFluor Violet 450 Anti-Human/Mouse KLRG-1 Antibody [2F1] (AGEL3111)

SKU:
AGEL3111
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Mouse
Host Species:
Syrian Hamster
Isotype:
Syrian Hamster IgG
Clone:
2F1
Conjugation:
AFViolet 450
$167 - $563
Frequently bought together:

Description

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GenieFluor Violet 450 Anti-Human/Mouse KLRG-1 Antibody [2F1]

The GenieFluor Violet 450 Anti-Human/Mouse KLRG1 Antibody (2F1) (AGEL3111) offered by AssayGenie is a cutting-edge tool for researchers delving into the complex world of immune responses and cellular interactions. This monoclonal antibody targets the KLRG1 protein, a cell surface receptor involved in immune regulation and the differentiation of immune cell populations. With its exceptional specificity for both human and mouse samples, this antibody opens up a world of possibilities for investigating KLRG1's role in various physiological and pathological processes. From immunology studies to cancer research, the GenieFluor Violet 450 Anti-Human/Mouse KLRG1 Antibody (2F1) (AGEL3111) provides a reliable and sensitive means of detecting and analyzing KLRG1 expression in diverse cell types.

KLRG1, a marker of T cell differentiation and exhaustion, has been linked to immune responses in conditions such as infection, autoimmunity, and cancer. By utilizing this antibody, researchers can gain valuable insights into how KLRG1 influences immune cell function and potentially uncover new therapeutic targets for manipulating immune responses in disease settings.Embark on your next research journey with the GenieFluor Violet 450 Anti-Human/Mouse KLRG1 Antibody (2F1) (AGEL3111) and unravel the mysteries of immune regulation at the cellular level.

Product Title:GenieFluor Violet 450 Anti-Human/Mouse KLRG-1 Antibody [2F1]
SKU:AGEL3111
Size:20 Tests, 100 Tests, 200 Tests
Clone No:2F1
Synonyms:MAFA; 2F1-Ag;
Host Species:Syrian Hamster
Reactivity:Human;Mouse
Application:FCM
Isotype:Syrian Hamster IgG
Isotype Control:Genie Fluor Violet 450 Syrian Hamster IgG Isotype Control[SHG-1]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q96E93 O88713
Gene ID:10219,50928
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag). KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3. It is composed of a homodimer of glycosylated 30-38 kD subunits. Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells. KLRG1 is also expressed on subsets of CD8+ and CD4+ cells, including CD4+ and CD8+ effector/memory cells, potent regulatory CD4+ T cells. KLRG1 may be involved in regulating NK cell homeostasis. KLRG17 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.

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