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GenieFluor Violet 450 Anti-Human/Mouse CD44 Antibody [IM7] (AGEL2735)

SKU:
AGEL2735
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Mouse
Host Species:
Rat
Isotype:
Rat IgG2b, κ
Clone:
IM7
Conjugation:
AFViolet 450
€199 - €409
Frequently bought together:

Description

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GenieFluor Violet 450 Anti-Human/Mouse CD44 Antibody [IM7]

The GenieFluor Violet 450 Anti-Human/Mouse CD44 Antibody (IM7) from AssayGenie (AG-EL2735) is a cutting-edge tool for the detection and analysis of CD44, a cell surface glycoprotein involved in cell adhesion, migration, and signaling. This highly specific antibody recognizes both human and mouse CD44 antigens, making it versatile for a wide range of research applications.The IM7 antibody, optimized and validated by AssayGenie, offers exceptional sensitivity and precision in immunofluorescence and flow cytometry experiments. By targeting the CD44 protein, researchers can gain insights into various cellular processes and pathways, including cancer metastasis, stem cell biology, and immune cell interactions.

CD44 is a multifunctional molecule with diverse roles in health and disease, making it a compelling target for investigation. Its involvement in inflammation, tissue regeneration, and tumor progression underscores the importance of studying CD44 dynamics in different biological contexts. With the GenieFluor Violet 450 Anti-Human/Mouse CD44 Antibody, researchers can dive deep into the intricate functions of CD44 and unravel its implications in various physiological and pathological conditions.

Product Title:GenieFluor Violet 450 Anti-Human/Mouse CD44 Antibody [IM7]
SKU:AGEL2735
Size:25µg, 100µg
Clone No:IM7
Synonyms:CD44 antigen;CD44;CDw44;Epican;Phagocytic glycoprotein 1;PGP-1;Phagocytic glycoprotein I;PGP-I;CD44;LHR; MDU2; MDU3; MIC4;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor Violet 450 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P15379 P16070
Gene ID:12505,960
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

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