The GenieFluor Violet 450 Anti-Human IgD Antibody (IA6-2) is a cutting-edge tool for researchers interested in studying the IgD protein in human samples. This antibody, specifically designed for detecting IgD, offers high specificity and sensitivity for use in various applications such as flow cytometry and immunofluorescence.IgD is a critical component of the immune system, functioning as a B-cell receptor and playing a crucial role in immune responses. By targeting IgD, researchers can gain insights into B-cell development, activation, and function, particularly in the context of immune disorders, infectious diseases, and autoimmune conditions.
The GenieFluor Violet 450 Anti-Human IgD Antibody (IA6-2) provides a reliable and validated tool for investigating IgD expression and localization in different cell types and tissues. Its versatility and accuracy make it an essential reagent for immunology studies and biomedical research aimed at understanding the complex interplay of the immune system and disease processes.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P01880
Gene ID:
3495
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
IgD, a member of the immunoglobulin (Ig) family, is expressed in naïve B cells. It has 3 Ig-like domains and exists in a transmembrane and a soluble form. In general, IgD is not secreted and usually its expression is lost after the Ig isotype switch. After antigen binding, IgD signals through the CD79a/CD79b (Igα/Igβ) heterodimer, resulting in the activation of the B cell.