The GenieFluor Violet 450 Anti-Human HLA-DR Antibody (L243) offered by Assay Genie is a cutting-edge tool for research in immunology and histocompatibility. This antibody is specifically designed to target the HLA-DR protein, a critical component of the human immune system. The highly reactive nature of the antibody ensures precise and accurate detection of HLA-DR in various cell types, enabling detailed analysis and investigation.HLA-DR is a key molecule involved in antigen presentation and immune response regulation. By targeting this protein with the GenieFluor Violet 450 Anti-Human HLA-DR Antibody (L243), researchers can gain valuable insights into the functioning of the immune system, particularly in the context of transplant rejection, autoimmune diseases, and infectious conditions.
The antibody's superior performance in assays such as flow cytometry and immunofluorescence makes it an essential tool for studies focused on understanding immunological processes at the molecular level.With its high specificity and sensitivity, the GenieFluor Violet 450 Anti-Human HLA-DR Antibody (L243) is poised to advance research in immunology, transplantation biology, and personalized medicine. Researchers seeking to unravel the complexities of immune responses and immune-related disorders will find this antibody indispensable in their quest for scientific discovery.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P01903 P01911
Gene ID:
3122,3123
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells.