The GenieFluor Violet 450 Anti-Human CD66b Antibody (G10F5) is a cutting-edge research tool designed for the detection and analysis of CD66b, a cell surface protein associated with immune responses and inflammation. This antibody, produced for human samples, is specifically tailored for immunofluorescence applications, enabling precise visualization and quantification of CD66b expression in a variety of cell types.CD66b, also known as CEACAM8, is a marker of neutrophils and plays a key role in neutrophil activation and migration during immune responses. Understanding the expression and function of CD66b is essential for deciphering the intricate mechanisms of the immune system, particularly in contexts such as infectious diseases, inflammatory disorders, and cancer research.
The GenieFluor Violet 450 Anti-Human CD66b Antibody provides researchers with a reliable tool to unravel the complexities of CD66b biology and its implications in various pathological conditions.With its high specificity and sensitivity, this antibody is a valuable asset for studies aiming to elucidate the role of CD66b in immune regulation and disease pathogenesis. By facilitating the visualization and analysis of CD66b expression patterns, researchers can gain valuable insights that may lead to the development of novel diagnostic and therapeutic approaches in the fields of immunology and oncology.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P31997
Gene ID:
1088
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD66b is a 95-100 kD glycosylphosphatidylinositol (GPI)-linked protein also known as CD67, CGM6, and NCA-95. CD66b is a member of the immunoglobulin superfamily, carcinoembryonic antigen (CEA)-like subfamily. CD66b, expressed on granulocytes, has been reported to induce activation in neutrophils and to be involved in heterophilic adhesion with CD66c.