The GenieFluor Violet 450 Anti-Human CD62L Antibody (Clone: DREG56) offered by Assay Genie is a cutting-edge immunology tool designed for precise detection and analysis of CD62L, a key cell adhesion molecule involved in immune cell trafficking. This antibody, optimized for use in flow cytometry applications, specifically targets the human CD62L protein, allowing for accurate identification and characterization of CD62L-expressing cells in various experimental settings.CD62L, also known as L-selectin, is a crucial molecule involved in the migration of lymphocytes to secondary lymphoid tissues and sites of inflammation. By targeting CD62L with the GenieFluor Violet 450 Anti-Human CD62L Antibody, researchers can delve into the intricate mechanisms of immune cell trafficking, homing, and activation.
The high specificity and sensitivity of this antibody make it an invaluable tool for studies focusing on immunology, inflammation, and immune-mediated disorders.Whether investigating immune cell populations in cancer research, autoimmune diseases, or inflammatory conditions, the GenieFluor Violet 450 Anti-Human CD62L Antibody provides researchers with a reliable and robust tool to advance their understanding of immune cell dynamics and function. Trust Assay Genie's expertise and innovation to propel your research forward in the realm of immunology and beyond.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P14151
Gene ID:
6402
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.