The GenieFluor Violet 450 Anti-Human CD61 Antibody (VI-PL2) offered by Assay Genie is a cutting-edge tool for researchers studying cell surface markers in human samples. This antibody specifically targets CD61, a protein involved in platelet function and thrombosis. With its high reactivity and specificity, the GenieFluor Violet 450 Anti-Human CD61 Antibody allows for precise detection and analysis of CD61 in a variety of cell types.CD61 is a crucial marker in understanding platelet biology, hemostasis, and vascular physiology. This antibody opens up new possibilities for research in areas such as cardiovascular diseases, thrombotic disorders, and hematological malignancies.
With its innovative GenieFluor Violet 450 technology, this antibody provides excellent sensitivity and signal-to-noise ratio, making it an ideal choice for fluorescence-based assays and multicolor flow cytometry experiments.By using the GenieFluor Violet 450 Anti-Human CD61 Antibody from Assay Genie, researchers can gain valuable insights into the role of CD61 in various physiological and pathological processes. This product is a valuable asset for immunologists, hematologists, and cell biologists seeking to advance their understanding of CD61 and its implications in human health and disease.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05106
Gene ID:
3690
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD61, also known as integrin β3 and glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is a member of the integrin family, associating with platelet gpIIb (CD41) to form CD41/CD61 complex and with integrin αV (CD51) to form αV/β3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes, and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF, and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblasts, macrophages, and some tumor cells involved in tumor metastasis, and in adenovirus infection through binding to RGD motif in extracellular matrix proteins.