The GenieFluor Violet 450 Anti-Human CD56 Antibody (5.1H11) offered by AssayGenie is a cutting-edge tool for researchers studying CD56, a cell surface marker associated with natural killer cells and neural tissues. This antibody, optimized for use in flow cytometry and immunofluorescence applications, exhibits high specificity and sensitivity towards human CD56, enabling precise detection and analysis in various cell populations.CD56, also known as neural cell adhesion molecule (NCAM), is a crucial molecule involved in cell adhesion, migration, and signal transduction. Its expression is key in identifying and studying natural killer cells, neural cell populations, and certain cancers.
The GenieFluor Violet 450 Anti-Human CD56 Antibody opens up avenues for detailed investigation into the role of CD56 in various physiological and pathological processes, including immune responses and neurological disorders.Researchers in immunology, oncology, neurobiology, and related fields can benefit from the exceptional performance and reliability of this antibody to advance their understanding of CD56 biology. By precisely targeting and detecting CD56, this antibody facilitates in-depth exploration of cellular interactions and functions, laying the groundwork for innovative research and potential therapeutic developments.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P13591
Gene ID:
4684
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD56 is a single transmembrane glycoprotein also known as NCAM (Neural Cell Adhesion Molecule), Leu-19, or NKH1. It is a member of the Ig superfamily. The 140 kD isoform is expressed on NK cells and NK-T cells. CD56 is also expressed in the brain (cerebellum and cortex) and at neuromuscular junctions. Certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal derived tumors, myelomas, and myeloid leukemias also express CD56. CD56 plays a role in homophilic and heterophilic adhesion via binding to itself or heparin sulfate.