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GenieFluor Violet 450 Anti-Human CD45 Antibody [HI30] (AGEL2995)

SKU:
AGEL2995
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
HI30
Conjugation:
AFViolet 450
€139 - €469
Frequently bought together:

Description

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GenieFluor Violet 450 Anti-Human CD45 Antibody [HI30]

The GenieFluor Violet 450 Anti-Human CD45 Antibody (HI30) offered by Assay Genie is a cutting-edge immunology research tool specially designed for the study of human CD45, a crucial cell surface marker involved in immune cell identification and activation. The antibody is engineered to exhibit high specificity and sensitivity in binding to CD45 protein, enabling precise detection and analysis in a variety of cell types and biological samples.CD45, a key component in immune cell signaling and function, is instrumental in regulating the activation and response of immune cells, playing a pivotal role in immune system function. By targeting CD45, researchers can gain valuable insights into immune cell behavior, differentiation, and activation states, therefore advancing our understanding of immune responses in various physiological and pathological conditions.

The GenieFluor Violet 450 Anti-Human CD45 Antibody (HI30) is meticulously validated for use in immunofluorescence and flow cytometry applications, providing researchers with a powerful tool to investigate immune cell populations, monitor immune responses, and explore the dynamics of immune cell interactions. With its exceptional performance and reliability, this antibody is an essential asset for studies in immunology, cancer research, and related fields, offering unparalleled flexibility and precision in experimental design and data interpretation. Unlock the potential of your research with the GenieFluor Violet 450 Anti-Human CD45 Antibody (HI30) from Assay Genie.

Product Title:GenieFluor Violet 450 Anti-Human CD45 Antibody [HI30]
SKU:AGEL2995
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HI30
Synonyms:Receptor-type tyrosine-protein phosphatase C;Ptprc;L-CA;Ly-5;T200;CD45;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor Violet 450 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P08575
Gene ID:5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.

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