The GenieFluor Violet 450 Anti-Human CD44 Antibody (Hermes-1) offered by Assay Genie is a cutting-edge tool for researchers studying CD44, a cell surface glycoprotein involved in cell adhesion and migration processes. This polyclonal antibody, optimized for human samples, is ideal for a range of applications including flow cytometry and immunofluorescence.CD44 plays a key role in cell-cell interactions, cell signaling, and migration, making it a significant target for investigation in various fields such as cancer, stem cell research, and inflammation.
The GenieFluor Violet 450 Anti-Human CD44 Antibody (Hermes-1) specifically recognizes the CD44 protein, enabling precise detection and analysis in different cell types.With its high specificity and sensitivity, this antibody provides researchers with a reliable tool to explore the functions of CD44 in both normal and pathological conditions. Its versatility and performance make it a valuable asset for studies aiming to unravel the complexities of CD44-mediated processes in biology and disease.
Genie Fluor Violet 450 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Genie FluorViolet 450
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P16070
Gene ID:
960
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from a low or mid level of intensity to high expression levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.