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GenieFluor Violet 450 Anti-Human CD40 Antibody [G28.5] (AGEL3346)

SKU:
AGEL3346
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, k
Clone:
G28.5
Conjugation:
AFViolet 450
€219 - €709
Frequently bought together:

Description

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GenieFluor Violet 450 Anti-Human CD40 Antibody [G28.5]

The GenieFluor Violet 450 Anti-Human CD40 Antibody (G28-5) is a cutting-edge tool for researchers studying the CD40 protein, an essential molecule involved in immune responses and cell signaling. This antibody, optimized for use in flow cytometry and immunofluorescence, exhibits high specificity and sensitivity in detecting CD40 in human samples.CD40 is a key receptor found on various immune cells, including B cells, dendritic cells, and macrophages, that plays a crucial role in activating immune responses and promoting communication between different cell types. By targeting CD40 with the GenieFluor Violet 450 Anti-Human CD40 Antibody (G28-5), researchers can accurately visualize and quantify CD40 expression, allowing for detailed analysis of immune cell interactions and signaling pathways.

In fields such as immunology, oncology, and infectious diseases, understanding the role of CD40 in modulating immune responses is of paramount importance. The GenieFluor Violet 450 Anti-Human CD40 Antibody (G28-5) provides researchers with a powerful tool to advance their studies, uncover novel insights into immune regulation, and develop targeted therapies for various disorders.

Product Title:GenieFluor Violet 450 Anti-Human CD40 Antibody [G28.5]
SKU:AGEL3346
Size:20 Tests, 100 Tests, 200 Tests
Clone No:G28.5
Synonyms:Bp50;CDw40;CD40L receptor;TNFRSF5;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor Violet 450 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P25942
Gene ID:958
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand).

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