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GenieFluor Violet 450 Anti-Human CD4 Antibody [SK3] (AGEL3450)

SKU:
AGEL3450
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, k
Clone:
SK3
Conjugation:
AFViolet 450
€199 - €829
Frequently bought together:

Description

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GenieFluor Violet 450 Anti-Human CD4 Antibody [SK3]

The Goat Anti-Human CD4 Antibody (SK3) from Assay Genie is a valuable tool for researchers studying the CD4 cell surface marker, a key player in immune response and cell signaling. This antibody, derived from goats, exhibits high specificity and sensitivity for detecting human CD4 antigen in various cell types and tissues.With its ability to bind specifically to the CD4 protein, the SK3 antibody enables the precise visualization and analysis of CD4-expressing cells, making it ideal for a range of applications including flow cytometry, immunohistochemistry, and immunofluorescence. Its reliable performance and consistent results make it a trusted reagent for studies in immunology, infectious diseases, and autoimmune disorders.

The CD4 molecule is essential for the proper functioning of the immune system, serving as a coreceptor for T cell activation. Its expression on helper T cells and regulatory T cells links it to important immune responses and disease mechanisms, including HIV infection, autoimmunity, and immunodeficiency disorders. By targeting CD4 with the SK3 antibody, researchers can gain valuable insights into the role of CD4 in health and disease, paving the way for new therapeutic strategies and interventions.

Product Title:GenieFluor Violet 450 Anti-Human CD4 Antibody [SK3]
SKU:AGEL3450
Size:20 Tests, 100 Tests, 200 Tests
Clone No:SK3
Synonyms:T-cell surface glycoprotein CD4;T-cell surface antigen T4/Leu-3;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor Violet 450 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P01730
Gene ID:920
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD4, also known as T4, is a 55 kD single-chain type I transmembrane glycoprotein expressed on most thymocytes, a subset of T cells, and monocytes/macrophages. CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4 has also been shown to interact with IL-16.

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