The GenieFluorâ„¢ Violet 450 Anti-Human CD326 Antibody (clone 9C4) offered by Assay Genie is a premium product designed for research applications involving the cell surface marker CD326, also known as EpCAM. This monoclonal antibody raised against human samples is ideal for flow cytometry and immunofluorescence studies, enabling accurate detection and analysis of CD326 expression in various cell types.CD326, a transmembrane glycoprotein, is widely used as a marker for epithelial cells and various carcinomas, making it a valuable tool for cancer research, stem cell studies, and investigations into epithelial cell biology.
The GenieFluorâ„¢ Violet 450 Anti-Human CD326 Antibody provides high specificity and sensitivity, allowing for reliable identification and quantification of CD326-expressing cells.Researchers in fields such as oncology, regenerative medicine, and developmental biology will benefit from the superior performance of this antibody in their experiments. With its high reactivity and versatility, the GenieFluorâ„¢ Violet 450 Anti-Human CD326 Antibody (clone 9C4) is a valuable asset for those exploring the roles of CD326 in health and disease. Trust Assay Genie for cutting-edge tools that enhance your research capabilities.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P16422
Gene ID:
4072
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD326 is also known as Ep-CAM, tumor associated calcium signal transducer 1, epithelial cell surface antigen, epithelial glycoprotein 2, EGP2, adenocarcinoma associated antigen, and TROP1. CD326 is a type I transmembrane protein containing six disulfide bridges and one THYRO domain. This cell surface glycosylated 40 kD protein is highly expressed in bone marrow, colon, lung, and most normal epithelial cells and is expressed on carcinomas of gastrointestinal origin. Recently, it has been reported that CD326 expression occurs during the early steps of erythrogenesis. CD326 functions as a homotypic calcium-independent cell adhesion molecule and is believed to be involved in carcinogenesis by its ability to induce genes involved in cellular metabolism and proliferation. CD326 antigen is an immunotherapeutic target for the treatment of human carcinomas.