The GenieFluor Violet 450 Anti-Human CD3 Antibody (OKT-3) offered by AssayGenie is a cutting-edge tool for research applications involving the CD3 antigen, a key marker of T cells. This antibody, specifically designed for use with human samples, is highly sensitive and specific, allowing for accurate detection and analysis of CD3 expression in various cell types. Its compatibility with flow cytometry and immunofluorescence techniques makes it an essential component for immunology studies, particularly those focusing on T cell function and activation.CD3 is an essential component of the T cell receptor complex, playing a crucial role in T cell activation and signaling. By targeting CD3 with the OKT-3 antibody, researchers can gain insights into T cell function, activation, and proliferation in both normal and pathological conditions.
This antibody's exceptional performance in flow cytometry applications enables precise quantification of CD3-expressing cells, offering valuable data for studies related to immunotherapy, infectious diseases, and autoimmune disorders.Overall, the GenieFluor Violet 450 Anti-Human CD3 Antibody (OKT-3) from AssayGenie is a reliable and versatile tool for researchers seeking to investigate T cell biology and immune responses in human samples. Its high specificity and sensitivity make it a valuable asset in the study of T cell-mediated immunity and the development of novel therapeutic strategies targeting T cell function.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P07766
Gene ID:
916
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3ε is a 20 kD chain of the CD3/T cell receptor (TCR) complex, which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T lymphocytes, NK T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation.