The GenieFluor Violet 450 Anti-Human CD19 Antibody (CB19) offered by AssayGenie is a cutting-edge tool for researchers studying CD19, a cell surface protein paramount in B cell development and function. This antibody, optimized for use in flow cytometry, immunofluorescence, and immunohistochemistry applications, provides unparalleled specificity and sensitivity for detecting CD19 expression in human samples.CD19 is a vital component of the B cell receptor complex and is expressed throughout B cell development, from early progenitors to mature B lymphocytes. Dysregulation of CD19 expression is implicated in various B cell-related disorders, including B cell malignancies and autoimmune diseases.
The availability of a high-quality antibody like GenieFluor Violet 450 Anti-Human CD19 Antibody (CB19) facilitates precise and reliable analysis of CD19 expression, enabling researchers to delve deeper into the mechanisms underlying these conditions.By targeting CD19, researchers can gain valuable insights into B cell biology, immune responses, and the development of targeted therapies for diseases involving B cell dysregulation. The versatility and reliability of the GenieFluor Violet 450 Anti-Human CD19 Antibody (CB19) make it an indispensable tool for advancing research in immunology, oncology, and autoimmune disorders.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P15391
Gene ID:
930
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD19 is a 95 kD type I transmembrane glycoprotein also known as B4. It is a member of the immunoglobulin superfamily expressed on B-cells (from pro-B to blastoid B cells, absent on plasma cells) and follicular dendritic cells. CD19 is involved in B cell development, activation, and differentiation. CD19 forms a complex with CD21 (CR2) and CD81 (TAPA-1), and functions as a BCR co-receptor.