The GenieFluor Violet 450 Anti-Human CD14 Antibody (M5E2) offered by Assay Genie is a premium research tool designed for scientists studying immune responses and cell surface molecules. This antibody is specifically tailored for detecting CD14, a key marker of monocytes and macrophages, in human samples. With its high reactivity and specificity, this antibody is ideal for a range of applications, including flow cytometry and immunofluorescence microscopy.CD14 is a pivotal receptor involved in innate immunity and inflammatory responses. By targeting CD14, researchers can gain insights into the function of immune cells and their interactions with pathogens or antigens.
This antibody’s reliability and sensitivity in detecting CD14 make it a valuable asset for studies related to infectious diseases, immunology, and inflammation.By utilizing the GenieFluor Violet 450 Anti-Human CD14 Antibody (M5E2), researchers can explore the role of CD14 in immune regulation, host defense mechanisms, and disease pathogenesis. This antibody’s precision and performance ensure accurate and reproducible results, enabling breakthrough discoveries in biomedical research.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P08571
Gene ID:
929
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens, and in the upregulation of adhesion molecules and expression of cytokines in monocytes and neutrophils.