The GenieFluor Red 780 Anti-Rat CD45 Antibody (OX-1) from AssayGenie (AGEL3017) is a powerful tool for researchers studying rat immune cells and hematopoietic stem cells. This polyclonal antibody, specifically designed for the detection of CD45, a key marker of hematopoietic cells, is highly reliable and effective in various immunological and cell biology applications.The anti-rat CD45 antibody is raised using advanced techniques and exhibits exceptional reactivity and specificity towards CD45, enabling precise detection and analysis of rat immune cell populations in experimental settings. Its performance is validated for use in a range of techniques, including flow cytometry, immunofluorescence, and immunohistochemistry, confirming its versatility and reliability for diverse research applications.CD45, also known as leukocyte common antigen, is a crucial regulator of immune cell activation and differentiation, making it a valuable target for investigating immune response mechanisms, cell signaling pathways, and hematopoietic development.
By utilizing the OX-1 anti-CD45 antibody from AssayGenie, researchers can gain deeper insights into the function and behavior of rat immune cells, leading to advancements in immunology, infectious disease research, and therapeutic development.With its high specificity, sensitivity, and validated performance, the GenieFluor Red 780 Anti-Rat CD45 Antibody (OX-1) is an indispensable tool for scientists exploring the complexities of rat immune cell biology and seeking to unravel the mechanisms underlying immune responses and hematopoiesis. Trust AssayGenie for quality antibodies that drive groundbreaking discoveries in immunology and beyond.
Product Title:
GenieFluor Red 780 Anti-Rat CD45 Antibody [OX-1]
SKU:
AGEL3017
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
OX-1
Synonyms:
Receptor-type tyrosine-protein phosphatase C;Leukocyte common antigen; LCA; T200; Ly-5;Ptprc;
Host Species:
Mouse
Reactivity:
Rat
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
Genie Fluor Red 780 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
Genie FluorRed 780
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P04157
Gene ID:
19265
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro.