The GenieFluor Red 780 Anti-Rat CD45 Antibody (OX-1) is a powerful tool for researchers studying rat immune cells and hematopoietic system. This antibody, developed by Assay Genie, specifically targets the CD45 antigen, a key marker for identifying leukocytes. With high specificity and sensitivity, this antibody is ideal for flow cytometry, immunofluorescence, and other immunological assays.CD45 is a transmembrane protein found on all nucleated hematopoietic cells, playing a crucial role in immune cell activation and signaling. The OX-1 antibody, optimized for rat samples, offers exceptional performance in detecting and analyzing CD45 expression in various tissues and cell types.
Its reliability and precision make it a valuable tool for immunologists, oncologists, and researchers exploring immunotherapy and immune-related diseases in rat models.By using the GenieFluor Red 780 Anti-Rat CD45 Antibody (OX-1), researchers can gain deeper insights into the role of CD45 in immune function, inflammation, and hematopoiesis. This antibody opens up new possibilities for investigating immune responses, monitoring disease progression, and developing targeted therapies in preclinical studies. Unlock the potential of rat CD45 research with this advanced antibody from Assay Genie.
Product Title:
GenieFluor Red 780 Anti-Rat CD45 Antibody [OX-1]
SKU:
AGEL3016
Size:
25µg, 100µg
Clone No:
OX-1
Synonyms:
Receptor-type tyrosine-protein phosphatase C;Leukocyte common antigen; LCA; T200; Ly-5;Ptprc;
Host Species:
Mouse
Reactivity:
Rat
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
Genie Fluor Red 780 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
Genie FluorRed 780
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P04157
Gene ID:
19265
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro.