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GenieFluor Red 780 Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5] (AGEL2988)

SKU:
AGEL2988
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2b, κ
Clone:
RB6-8C5
Conjugation:
AFRed 780
€189
Frequently bought together:

Description

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GenieFluor Red 780 Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5]

The GenieFluor Red 780 Anti-Mouse Ly-6G/Ly-6C (GR-1) Antibody (RB6-8C5) [AGEL2988] is a powerful tool for researchers studying immune cell populations in mice. This monoclonal antibody specifically targets Ly-6G and Ly-6C, also known as GR-1, providing detailed insights into the distribution and function of these markers in various experimental settings.Ly-6G and Ly-6C are widely used surface markers for identifying and characterizing myeloid-derived suppressor cells (MDSCs) and granulocytes in mouse models. The RB6-8C5 antibody, conjugated to the GenieFluor Red 780 fluorophore, offers high sensitivity and specificity for flow cytometry and immunofluorescence applications. Its reliable performance and excellent signal-to-noise ratio make it a valuable tool for investigating immune cell dynamics and responses in diverse research areas, including immunology, inflammation, infection, and cancer.

With this antibody, researchers can delve deeper into the roles of Ly-6G and Ly-6C in immune regulation, inflammation, and disease progression. By accurately detecting and quantifying these critical markers, scientists can enhance their understanding of immune cell populations and pave the way for innovative therapeutic strategies targeting MDSCs and granulocytes. Unlock the potential of your mouse model studies with the GenieFluor Red 780 Anti-Mouse Ly-6G/Ly-6C (GR-1) Antibody (RB6-8C5) [AGEL2988] from Assay Genie.

Product Title:GenieFluor Red 780 Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5]
SKU:AGEL2988
Size:25µg, 100µg
Clone No:RB6-8C5
Synonyms:Gr-1;Gr1;Ly-6G/Ly-6C;Ly6G/Ly6C;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor Red 780 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie FluorRed 780
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P35461 P0CW03
Gene ID:546644 ,17067
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.

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