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GenieFluor Red 780 Anti-Mouse/Human CD11b Antibody [M1/70] (AGEL2963)

SKU:
AGEL2963
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Mouse
Host Species:
Rat
Isotype:
Rat IgG2b, κ
Clone:
M1/70
Conjugation:
AFRed 780
$131 - $299
Frequently bought together:

Description

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GenieFluor Red 780 Anti-Mouse/Human CD11b Antibody [M1/70]

The GenieFluor Red 780 Anti-Mouse/Human CD11b Antibody (M1/70) is a cutting-edge research tool designed for the precise detection and analysis of CD11b, a key cell surface marker involved in immune response regulation. This high-quality antibody, specifically developed for use in mouse and human samples, has been rigorously validated for accuracy and reliability in various applications, including flow cytometry, immunofluorescence, and immunohistochemistry.CD11b, also known as integrin alpha M, is a crucial molecule expressed on the surface of immune cells such as monocytes, macrophages, and granulocytes. Its role in mediating cell adhesion and migration, as well as phagocytosis and immune activation, makes it a significant target for investigating immune system functions in health and disease.

By specifically binding to CD11b, the M1/70 antibody enables researchers to explore the dynamics of this important protein in different cell types and biological contexts, providing valuable insights into immune responses, inflammation, and disease pathogenesis.Whether studying inflammatory disorders, infectious diseases, or cancer immunology, the GenieFluor Red 780 Anti-Mouse/Human CD11b Antibody (M1/70) offers unparalleled sensitivity and specificity, empowering researchers to delve deeper into the complex mechanisms underlying immune regulation. Unlock the potential of your research with this innovative antibody and uncover new possibilities in the field of immunology and beyond.

Product Title:GenieFluor Red 780 Anti-Mouse/Human CD11b Antibody [M1/70]
SKU:AGEL2963
Size:50 Tests, 100 Tests, 200 Tests
Clone No:M1/70
Synonyms:Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor Red 780 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie FluorRed 780
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P05555 P11215
Gene ID:16409,3684
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

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