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GenieFluor Red 780 Anti-Mouse F4/80 Antibody [CI:A3-1] (AGEL3115)

SKU:
AGEL3115
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2b, κ
Clone:
CI:A3-1
Conjugation:
AFRed 780
€199 - €539
Frequently bought together:

Description

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GenieFluor Red 780 Anti-Mouse F4/80 Antibody [CI:A3-1]

The GenieFluor Red 780 Anti-Mouse F4/80 Antibody (CI:A3-1) is a highly specific antibody designed for research applications involving the F4/80 protein, a marker of mouse macrophages and related cell types. This antibody, raised in rabbits, demonstrates high reactivity and specificity towards mouse samples, making it an excellent tool for immunofluorescence and immunohistochemistry studies.Macrophages are essential components of the immune system, playing crucial roles in inflammation, tissue repair, and immune response modulation. The F4/80 protein is a well-established marker for identifying and studying these key immune cells in various tissues and disease contexts.

By targeting the F4/80 protein, researchers can accurately visualize and analyze macrophage populations, allowing for detailed investigations into their functions and interactions within the immune system.The GenieFluor Red 780 Anti-Mouse F4/80 Antibody (CI:A3-1) offers researchers a reliable and sensitive tool for studying macrophages in mouse models, providing valuable insights into immune responses, inflammatory processes, and disease mechanisms. Its specificity, sensitivity, and compatibility with various experimental techniques make it an indispensable reagent for studies in immunology, cancer biology, and related fields.

Product Title:GenieFluor Red 780 Anti-Mouse F4/80 Antibody [CI:A3-1]
SKU:AGEL3115
Size:25µg, 100µg
Clone No:CI:A3-1
Synonyms:Adhesion G protein-coupled receptor E1;Adgre1;Cell surface glycoprotein F4/80;EGF-like module receptor 1;Adgre1;Emr1; Gpf480;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor Red 780 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie FluorRed 780
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q61549
Gene ID:13733
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:F4/80 is a 160 kD glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which is expressed on the majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen (but not on the macrophages located in T cell areas of the spleen, lymph node and Peyer's patch), Kuffer cells, Langerhans cells, and bone marrow stromal cells. F4/80 has also been shown on a subset of dendritic cells. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for induction of CD8+ T cells-mediated peripheral tolerance.

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