GenieFluor Red 780 Anti-Mouse F4/80 Antibody [CI:A3-1]
The GenieFluor Red 780 Anti-Mouse F4/80 Antibody (CI:A3-1) is a cutting-edge tool designed for researchers studying macrophages and immune responses in mouse models. This high-quality antibody, generated for mouse F4/80 protein detection, offers exceptional specificity and sensitivity for immunofluorescence and flow cytometry applications, allowing for precise identification and analysis of macrophage populations.F4/80 is a well-established marker for mouse macrophages, playing a crucial role in tissue homeostasis, inflammation, and immune regulation. By targeting the F4/80 protein, researchers can gain insights into the function and distribution of macrophages in various biological processes, including immune responses, wound healing, and disease progression.
With its superior performance and reliability, the GenieFluor Red 780 Anti-Mouse F4/80 Antibody (CI:A3-1) from Assay Genie provides a valuable tool for investigating macrophage biology and understanding their impact on the immune system. Whether studying inflammatory diseases, tumor-associated macrophages, or immune cell interactions, this antibody facilitates accurate and detailed analysis, contributing to advancements in immunology and biomedical research.
Product Title:
GenieFluor Red 780 Anti-Mouse F4/80 Antibody [CI:A3-1]
Genie Fluor Red 780 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
Genie FluorRed 780
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q61549
Gene ID:
13733
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
F4/80 is a 160 kD glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which is expressed on the majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen (but not on the macrophages located in T cell areas of the spleen, lymph node and Peyer's patch), Kuffer cells, Langerhans cells, and bone marrow stromal cells. F4/80 has also been shown on a subset of dendritic cells. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for induction of CD8+ T cells-mediated peripheral tolerance.