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GenieFluor Red 780 Anti-Mouse CD8a Antibody [53-6.7] (AGEL2975)

SKU:
AGEL2975
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, κ
Clone:
53-6.7
Conjugation:
AFRed 780
$215 - $491
Frequently bought together:

Description

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GenieFluor Red 780 Anti-Mouse CD8a Antibody [53-6.7]

The GenieFluor Red 780 Anti-Mouse CD8a Antibody (clone 53-6.7) (AGEL2975) from Assay Genie is a highly specific and sensitive tool for studying CD8a expression in mouse samples. This monoclonal antibody specifically targets the CD8a protein, a cell surface glycoprotein expressed by cytotoxic T cells and some dendritic cells.CD8a is a crucial marker for identifying cytotoxic T cells, which play a key role in the immune response against infected or cancerous cells. By targeting CD8a, this antibody enables researchers to accurately detect and quantify these important immune cell populations in various experimental settings.

This antibody is ideal for applications such as flow cytometry, immunohistochemistry, and immunofluorescence, providing valuable insights into the distribution and function of CD8a-positive cells.With its high specificity and sensitivity, the GenieFluor Red 780 Anti-Mouse CD8a Antibody (clone 53-6.7) (AGEL2975) is a valuable tool for immunology research, cancer immunotherapy studies, and investigations into immune responses in various disease models. Trust Assay Genie's reliable reagents to advance your research and uncover new insights into the complex world of immune cell biology.

Product Title:GenieFluor Red 780 Anti-Mouse CD8a Antibody [53-6.7]
SKU:AGEL2975
Size:25µg, 100µg
Clone No:53-6.7
Synonyms:T-cell surface glycoprotein CD8 alpha chain;CD8A;T-lymphocyte differentiation antigen T8/Leu-2;MAL;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor Red 780 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie FluorRed 780
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P01731
Gene ID:12525
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.

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