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GenieFluor Red 780 Anti-Mouse CD49b Antibody [DX5] (AGEL3321)

SKU:
AGEL3321
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgM, k
Clone:
DX5
Conjugation:
AFRed 780
€199 - €409
Frequently bought together:

Description

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GenieFluor Red 780 Anti-Mouse CD49b Antibody [DX5]

The GenieFluor Red 780 Anti-Mouse CD49b Antibody (DX5) from Assay Genie (AGEL3321) is a powerful tool for researchers studying immune responses and cell surface markers in mice. This antibody specifically targets CD49b, a molecule involved in cell adhesion and migration processes within the immune system. By binding to CD49b, the antibody enables precise detection and analysis of this protein in various cell types, making it an ideal choice for immunology and cell biology studies.CD49b, also known as DX5, is a marker that plays a crucial role in identifying and characterizing subsets of immune cells, particularly natural killer (NK) cells and some T cell populations. Understanding the expression and function of CD49b is essential for unraveling the mechanisms underlying immune responses, particularly in the context of immune surveillance, inflammation, and infection.

The GenieFluor Red 780 Anti-Mouse CD49b Antibody provides researchers with a reliable tool to investigate the role of CD49b in diverse biological processes, offering valuable insights into immune system function and potential therapeutic targets.Powered by Assay Genie's expertise in antibody development and validation, this antibody ensures high specificity and sensitivity in detecting mouse CD49b, facilitating reliable and reproducible experimental results. Whether studying immune cell populations in normal physiology or disease models, researchers can rely on this antibody to enhance their understanding of immune regulation and function in a mouse model system.

Product Title:GenieFluor Red 780 Anti-Mouse CD49b Antibody [DX5]
SKU:AGEL3321
Size:25µg, 100µg
Clone No:DX5
Synonyms:Integrin alpha-2;CD49 antigen-like family member B;Collagen receptor;Platelet membrane glycoprotein Ia;GPIa;VLA-2 subunit alpha;CD49b;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Form:Liquid
Conjugation:Genie FluorRed 780
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q62469
Gene ID:16398
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

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