GenieFluor Red 780 Anti-Mouse CD49b Antibody [DX5]
The GenieFluor Red 780 Anti-Mouse CD49b Antibody (DX5) is a versatile tool designed for researchers studying mouse CD49b, a key molecule involved in immune cell adhesion and migration. This antibody, developed by Assay Genie, offers high specificity and sensitivity for detecting CD49b in various experimental settings.CD49b, also known as DX5, is a critical integrin receptor expressed on natural killer cells and subsets of T cells. Its role in immune cell function and trafficking makes it a vital target for investigating immune responses, particularly in the context of infections, inflammation, and cancer.
By using this antibody, researchers can efficiently label and analyze CD49b-expressing cells in different biological samples, facilitating a deeper understanding of immune cell dynamics.Whether you are exploring immune cell interactions, studying tumor-infiltrating lymphocytes, or investigating immune responses in disease models, the GenieFluor Red 780 Anti-Mouse CD49b Antibody (DX5) provides a reliable tool for your research needs. Trust in its quality and specificity to advance your studies in immunology, oncology, and beyond.
Product Title:
GenieFluor Red 780 Anti-Mouse CD49b Antibody [DX5]
SKU:
AGEL3320
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
DX5
Synonyms:
Integrin alpha-2;CD49 antigen-like family member B;Collagen receptor;Platelet membrane glycoprotein Ia;GPIa;VLA-2 subunit alpha;CD49b;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgM, κ
Form:
Liquid
Conjugation:
Genie FluorRed 780
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q62469
Gene ID:
16398
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.