GenieFluor Red 780 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]
The GenieFluor Red 780 Anti-Mouse CD45R/B220 Antibody (RA3-6B2) from AssayGenie is a cutting-edge tool designed for precise research applications in immunology. This antibody, specifically targeting the CD45R/B220 protein expressed on mouse immune cells, offers exceptional specificity and sensitivity for flow cytometry and immunofluorescence assays.With its remarkable binding affinity to CD45R/B220, this antibody enables accurate identification and analysis of B cells in mouse samples, providing researchers with valuable insights into immune responses, B cell development, and disease mechanisms.
The GenieFluor Red 780 Anti-Mouse CD45R/B220 Antibody is a reliable reagent that ensures consistent and reproducible results, making it an essential component for studies focusing on immune cell characterization and function in various experimental settings.Whether investigating the role of B cells in infectious diseases, autoimmune disorders, or immunotherapy, this high-quality antibody from AssayGenie serves as a key tool for advancing scientific knowledge and driving discoveries in immunological research.
Product Title:
GenieFluor Red 780 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]
SKU:
AGEL2984
Size:
25µg, 100µg
Clone No:
RA3.3A 1/6.1
Synonyms:
B220;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgM, κ
Form:
Liquid
Conjugation:
Genie FluorRed 780
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Gene ID:
19264,5788
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.