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GenieFluor Red 780 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1] (AGEL2982)

SKU:
AGEL2982
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgM, κ
Clone:
RA3.3A 1/6.1
Conjugation:
AFRed 780
€159
Frequently bought together:

Description

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GenieFluor Red 780 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]

The GenieFluor Red 780 Anti-Mouse CD45R/B220 Antibody (RA3-6B2) is a powerful tool designed for researchers studying mouse immune cells expressing the CD45R/B220 molecule. This antibody, developed by Assay Genie, is highly specific and sensitive, allowing for precise detection and analysis in a variety of experimental settings.CD45R, also known as B220, is a common marker for B cells and a subset of T cells in mice. The RA3-6B2 antibody binds specifically to CD45R/B220, enabling researchers to identify and characterize these cell populations in immunology research. Its use has been validated in techniques such as flow cytometry and immunofluorescence, making it a versatile tool for investigating immune responses and cell populations in mouse models.

By targeting CD45R/B220, researchers can gain insights into the function and behavior of B cells and specific T cell subtypes in immune-mediated processes. This antibody is a valuable resource for studies focused on immunology, inflammation, autoimmune diseases, and cancer research in mouse models. Its high specificity and reliability make it an essential component in understanding the complex interactions within the immune system and developing targeted therapeutic approaches.

Product Title:GenieFluor Red 780 Anti-Mouse CD45R/B220 Antibody [RA3.3A 1/6.1]
SKU:AGEL2982
Size:50 Tests, 100 Tests, 200 Tests
Clone No:RA3.3A 1/6.1
Synonyms:B220;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Form:Liquid
Conjugation:Genie FluorRed 780
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Gene ID:19264,5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity.

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