The GenieFluor Red 780 Anti-Mouse CD3 Antibody (17A2, AGEL3053) is a highly specific immunological tool designed for research involving mouse CD3, a crucial marker for T-cell activation and function. This antibody, produced by AssayGenie, is optimized for use in various applications, including flow cytometry, immunofluorescence, and immunohistochemistry.CD3 is a key component of the T-cell receptor complex that plays a pivotal role in T-cell activation and signaling. The GenieFluor Red 780 Anti-Mouse CD3 Antibody specifically targets the CD3 antigen in mouse samples, enabling accurate detection and analysis of T-cell populations in research studies. Its high reactivity and specificity make it an essential tool for immunologists, oncologists, and researchers studying immune responses in various disease contexts.
By utilizing the GenieFluor Red 780 Anti-Mouse CD3 Antibody, researchers can effectively investigate T-cell activation, differentiation, and function in both normal and pathological conditions. This antibody is a valuable resource for studies aiming to unravel the complexities of immune responses, immunotherapy development, and the pathogenesis of immune-related disorders.Overall, the GenieFluor Red 780 Anti-Mouse CD3 Antibody offers researchers a reliable and robust solution for exploring the intricacies of T-cell biology and its implications in health and disease.
Product Title:
GenieFluor Red 780 Anti-Mouse CD3 Antibody [17A2]
SKU:
AGEL3053
Size:
25µg, 100µg
Clone No:
17A2
Synonyms:
T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain;CD3E/D/G/Z;CD3e/d/g/z;CD3E/D/G/Z;CD3;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
Genie Fluor Red 780 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
Genie FluorRed 780
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P04235 P11942 P22646 P24161
Gene ID:
12502
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.