GenieFluor Red 780 Anti-Mouse CD14 Antibody [Sa14-2]
The GenieFluor Red 780 Anti-Mouse CD14 Antibody (SA14-2, AGEL3119) is a powerful tool for researchers studying mouse CD14, a key receptor involved in the recognition of various pathogens and immune responses. This antibody, optimized for use in flow cytometry and immunofluorescence applications, specifically binds to mouse CD14, allowing for precise detection and analysis in diverse experimental settings.CD14 is a crucial component of the innate immune system, facilitating the recognition of bacterial lipopolysaccharides and other microbial molecules. Its activation triggers inflammatory responses and is integral to the body's defense mechanisms against infections.
The GenieFluor Red 780 Anti-Mouse CD14 Antibody provides researchers with a reliable means to study and manipulate CD14 expression, offering insights into immune system function, inflammatory processes, and potential therapeutic interventions.With its high specificity and sensitivity, this antibody enables accurate identification and characterization of CD14-expressing cells in a range of biological samples. Whether investigating innate immune responses, studying host-pathogen interactions, or exploring immune cell activation dynamics, the GenieFluor Red 780 Anti-Mouse CD14 Antibody is a valuable tool for advancing immunology and infectious disease research.
Product Title:
GenieFluor Red 780 Anti-Mouse CD14 Antibody [Sa14-2]
SKU:
AGEL3119
Size:
25µg, 100µg
Clone No:
Sa14-2
Synonyms:
CD 14;Myeloid cell-specific leucine-rich glycoprotein;Monocyte differentiation antigen CD14;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
Genie Fluor Red 780 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Genie FluorRed 780
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P10810
Gene ID:
12475
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed on macrophages, dendritic cells, Kupffer cells, hepatocytes, and granulocytes. As a high-affinity receptor for LPS-LBP (LPS-binding protein) complex, CD14, in association with Toll-like Receptor 4 (TLR4) or 2 (TLR2), is involved in the clearance of gram-negative pathogens.