GenieFluor Red 780 Anti-Mouse CD11c Antibody [N418]
The GenieFluor Red 780 Anti-Mouse CD11c Antibody (N418) is a powerful tool for researchers studying immune responses in mice. This antibody, specifically designed for detecting CD11c, a cell surface marker found on dendritic cells, offers high reactivity and sensitivity in various experimental applications.CD11c is a crucial molecule involved in the function of dendritic cells, which play a key role in initiating and regulating immune responses. By specifically targeting CD11c, researchers can investigate the role of dendritic cells in immune system processes, inflammation, and immune-related disorders in mouse models.
Validated for use in immunofluorescence and flow cytometry, the GenieFluor Red 780 Anti-Mouse CD11c Antibody (N418) provides reliable and accurate results for analyzing CD11c expression levels in different cell types and tissues. Its robust performance makes it an essential tool for immunology research, vaccine development, and understanding the mechanisms of immune responses in mouse models.
Product Title:
GenieFluor Red 780 Anti-Mouse CD11c Antibody [N418]
SKU:
AGEL3351
Size:
25µg, 100µg
Clone No:
N418
Synonyms:
Integrin alpha-X;Itgax;CD11 antigen-like family member C;Leukocyte adhesion receptor p150+95;CD11c;
Host Species:
Armenian Hamster
Reactivity:
Mouse
Application:
FCM
Isotype:
Armenian Hamster IgG
Isotype Control:
Genie Fluor Red 780 Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
Genie FluorRed 780
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
Q9QXH4
Gene ID:
16411
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54.