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GenieFluor Red 780 Anti-Human/Mouse CD44 Antibody [IM7] (AGEL3064)

SKU:
AGEL3064
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Mouse
Host Species:
Rat
Isotype:
Rat IgG2b, κ
Clone:
IM7
Conjugation:
AFRed 780
€199 - €639
Frequently bought together:

Description

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GenieFluor Red 780 Anti-Human/Mouse CD44 Antibody [IM7]

The GenieFluor Red 780 Anti-Human/Mouse CD44 Antibody (IM7) is a cutting-edge research tool designed for the precise detection and analysis of CD44, a cell surface glycoprotein involved in numerous cellular processes including cell adhesion, migration, and signaling. This highly specific antibody raised against CD44 in both human and mouse samples offers exceptional sensitivity and selectivity for a wide range of applications, particularly in flow cytometry and immunofluorescence.CD44, a multifunctional molecule known for its involvement in cell-cell interactions and cell-matrix adhesion, plays a crucial role in various physiological and pathological processes, such as inflammation, tissue regeneration, and cancer metastasis. By targeting CD44 with the GenieFluor Red 780 Anti-Human/Mouse CD44 Antibody (IM7), researchers can gain insights into the complex functions of CD44 in different cell types and disease contexts, paving the way for innovative studies in immunology, oncology, and regenerative medicine.

With its advanced fluorescence properties, high specificity for CD44 detection, and compatibility with diverse experimental techniques, the GenieFluor Red 780 Anti-Human/Mouse CD44 Antibody (IM7) is an invaluable asset for scientists seeking to unravel the roles of CD44 in health and disease. Harness the power of this innovative antibody to elevate your research endeavors and unlock new discoveries in the dynamic field of molecular and cellular biology.

Product Title:GenieFluor Red 780 Anti-Human/Mouse CD44 Antibody [IM7]
SKU:AGEL3064
Size:20 Tests, 100 Tests, 200 Tests
Clone No:IM7
Synonyms:CD44 antigen;CD44;CDw44;Epican;Phagocytic glycoprotein 1;PGP-1;Phagocytic glycoprotein I;PGP-I;CD44;LHR; MDU2; MDU3; MIC4;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor Red 780 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie FluorRed 780
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P15379 P16070
Gene ID:12505,960
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

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