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GenieFluor Red 780 Anti-Human CD86 Antibody [BU63] (AGEL3318)

SKU:
AGEL3318
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, k
Clone:
BU63
Conjugation:
AFRed 780
€199 - €629
Frequently bought together:

Description

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GenieFluor Red 780 Anti-Human CD86 Antibody [BU63]

The GenieFluor Red 780 Anti-Human CD86 Antibody (BU63) is a cutting-edge tool for researchers delving into the intricacies of the CD86 protein, a crucial regulator of immune responses. This antibody, meticulously developed by AssayGenie, is optimized for exceptional reactivity with human samples, ensuring reliable and accurate results in a variety of experimental setups.With a specific affinity for the CD86 protein, this antibody facilitates precise detection and analysis of CD86 expression in diverse cell types, making it an invaluable asset for studies in immunology and related fields. By targeting CD86, a key player in immune activation and co-stimulation, researchers can uncover insights into immune cell interactions, T-cell activation, and immune system modulation.The CD86 protein, also known as B7-2, serves as a vital co-stimulatory molecule in the immune system, playing a pivotal role in regulating T-cell responses and shaping immune activation.

Understanding the functions and regulatory mechanisms of CD86 is essential in unraveling the complexities of immune-mediated diseases, including autoimmune disorders, infectious diseases, and transplantation immunology.By harnessing the power of the GenieFluor Red 780 Anti-Human CD86 Antibody (BU63), researchers can deepen their understanding of immune signaling pathways, develop novel therapeutic strategies, and advance the field of immunology towards innovative breakthroughs. Trust AssayGenie's antibody expertise to elevate your research endeavors and unlock the mysteries of immune regulation through the lens of CD86 biology.

Product Title:GenieFluor Red 780 Anti-Human CD86 Antibody [BU63]
SKU:AGEL3318
Size:20 Tests, 100 Tests, 200 Tests
Clone No:BU63
Synonyms:T-lymphocyte activation antigen CD86;Cd86;Activation B7-2 antigen;Early T-cell costimulatory molecule 1;ETC-1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor Red 780 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie FluorRed 780
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P42081
Gene ID:942
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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