The GENIEFluor Red 780 Anti-Human CD73 Antibody (AD2) from Assay Genie is a highly specific and sensitive tool for targeting CD73, an important cell surface enzyme involved in immune regulation and inflammation modulation. This polyclonal antibody is specially designed for research applications involving human samples, offering reliable and reproducible results in a variety of experimental settings.CD73, also known as ecto-5'-nucleotidase, plays a crucial role in purinergic signaling and adenosine production, influencing immune responses and tissue homeostasis. By targeting CD73 with the GENIEFluor Red 780 Anti-Human CD73 Antibody, researchers can detect and analyze the expression of this key protein in different cell types and tissues.
This antibody is ideal for use in techniques such as immunofluorescence, flow cytometry, and immunohistochemistry, providing valuable insights into the function and localization of CD73 in various biological systems.The GENIEFluor Red 780 Anti-Human CD73 Antibody (AD2) opens up new possibilities for investigating the role of CD73 in immune-mediated diseases, cancer biology, and therapeutic development. With its high specificity and sensitivity, this antibody is a valuable tool for scientists and researchers seeking to unravel the complexities of immune regulation and inflammatory processes, advancing our understanding of disease mechanisms and potential treatment strategies.
Genie Fluor Red 780 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
Genie FluorRed 780
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P21589
Gene ID:
4907
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD73 is a 70 kD glycophosphatidylinositol (GPI)-linked 5'-nucleotidase, which is also known as ecto-5'-nucleotidase. It converts adenosine monophosphate (AMP) to adenosine. CD73 is expressed on subsets of T and B cells, mesenchymal stem cells, follicular dendritic cells, endothelial cells, and epithelial cells. It has been reported that CD73 costimulates T cell activation, and mediates adhesion of lymphocytes to follicular dendritic cells and endothelial cells.