GenieFluor Red 780 Anti-Human CD62L Antibody [DREG56]
The GenieFluor Red 780 Anti-Human CD62L Antibody (DREG56) offered by AssayGenie is a cutting-edge tool for researchers delving into the cellular dynamics of immune responses. This antibody, specifically targeting CD62L, a key adhesion molecule involved in lymphocyte trafficking and activation, is meticulously designed to provide high specificity and sensitivity in detecting human CD62L in various experimental setups.Through a rigorous development process, the GenieFluor Red 780 Anti-Human CD62L Antibody (DREG56) has been engineered to excel in applications such as flow cytometry, immunofluorescence, and immunohistochemistry. Its superior performance in recognizing CD62L enables precise identification and analysis of lymphocyte subsets expressing this crucial marker, facilitating in-depth investigations into immune cell behavior and function.
With its validated reactivity with human samples, the GenieFluor Red 780 Anti-Human CD62L Antibody (DREG56) ensures reliable and reproducible results, making it a valuable asset for studies encompassing immunology, inflammation, and related fields. By unlocking the intricacies of CD62L-mediated processes, researchers can broaden their understanding of immune cell interactions and potentially uncover new therapeutic targets for diseases involving immune dysregulation.In conclusion, the GenieFluor Red 780 Anti-Human CD62L Antibody (DREG56) stands at the forefront of innovative research tools, empowering scientists to delve deeper into the complexities of immune responses and pave the way for advancements in immunotherapy, autoimmune disease treatment, and beyond.
Product Title:
GenieFluor Red 780 Anti-Human CD62L Antibody [DREG56]
SKU:
AGEL2961
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
DREG56
Synonyms:
L-selectin;Sell;CD62 antigen-like family member L;LAM-1;LECAM1;Lymph node homing receptor;Ly-22; CD62L;Lnhr;Ly22;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
Genie Fluor Red 780 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
Genie FluorRed 780
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P14151
Gene ID:
6402
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.