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GenieFluor Red 780 Anti-Human CD45 Antibody [HI30] (AGEL2996)

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SKU AGEL2996
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG1, κ
Clone HI30
Conjugation AFRed 780
€65 - €250
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Description

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GenieFluor Red 780 Anti-Human CD45 Antibody [HI30]

The GenieFluor Red 780 Anti-Human CD45 Antibody (HI30) is a cutting-edge tool designed for researchers studying human CD45, a key protein present on the surface of immune cells. This antibody, optimized for fluorescence-based techniques, demonstrates high specificity and sensitivity in identifying CD45 in various biological samples. CD45, also known as the leukocyte common antigen, plays a pivotal role in immune cell signaling and activation. Its expression pattern and function make it an essential marker for identifying different immune cell populations and monitoring immune responses. The GenieFluor Red 780 Anti-Human CD45 Antibody (HI30) provides researchers with a reliable means to visualize and quantify CD45-expressing cells in flow cytometry, immunofluorescence, and other fluorescence-based assays.

With its superior performance and specificity, the GenieFluor Red 780 Anti-Human CD45 Antibody (HI30) is a valuable tool for studies focusing on immune cell biology, inflammation, immunotherapy, and various disease models. Researchers can leverage this antibody to gain insights into immune cell dynamics, immune system dysregulation, and disease progression, ultimately advancing our understanding of immune-related disorders and therapeutic interventions.

Product Title:GenieFluor Red 780 Anti-Human CD45 Antibody [HI30]
SKU:AGEL2996
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HI30
Synonyms:Receptor-type tyrosine-protein phosphatase C;Ptprc;L-CA;Ly-5;T200;CD45;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor Red 780 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie FluorRed 780
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P08575
Gene ID:5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.

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