The GenieFluorâ„¢ Red 780 Anti-Human CD39 Antibody (A1) from Assay Genie is a highly specific and sensitive tool designed for the detection of CD39, an important cell surface enzyme involved in immune regulation and inflammation. This polyclonal antibody is raised in rabbits and exhibits strong reactivity towards human samples, making it an excellent choice for a wide range of research applications.CD39, also known as ectonucleoside triphosphate diphosphohydrolase 1, plays a key role in purinergic signaling and immune response modulation. By targeting CD39 with this antibody, researchers can accurately detect and analyze the expression of this molecule in various cell types, providing valuable insights into its function and potential therapeutic implications.This antibody is validated for use in techniques such as immunofluorescence, flow cytometry, and immunohistochemistry, offering versatility in experimental approaches.
With its ability to bind specifically to CD39, researchers can investigate its involvement in immune-related disorders, inflammatory conditions, and other diseases where purinergic signaling is implicated.Investigating the role of CD39 with the GenieFluorâ„¢ Red 780 Anti-Human CD39 Antibody (A1) can lead to a deeper understanding of immune regulation and provide valuable information for the development of novel therapeutic strategies in areas like cancer research, autoimmune diseases, and inflammatory disorders. Trust in Assay Genie's reliable antibody for your research needs and unlock the potential of CD39 in advancing scientific knowledge and medical innovations.
Product Title:
GenieFluor Red 780 Anti-Human CD39 Antibody [A1]
SKU:
AGEL3326
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
A1
Synonyms:
SPG64;NTPDase1;ATPDase;CD 39;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
Genie Fluor Red 780 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
Genie FluorRed 780
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P49961
Gene ID:
953
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
Human CD39 is an integral membrane protein with two transmembrane domains. It exists as a homotetramer. Expression of CD39 is found on activated lymphocytes, a subset of T cells and B cells, and dendritic cells with weak staining on monocytes and granulocytes. CD39 and CD73 have been found on regulatory T cells, specifically the effector/memory like T cells. CD39 can hydrolyze both nucleoside triphosphates and diphosphates. CD39 is the dominant ecto nucleotidase of vascular and placental trophoblastic tissues and appears to modulate the functional expression of type 2 purinergic (P2) G protein coupled receptors (GPCRs). CD39 has intrinsic ecto-ATPase activity. Expression of CD39 is induced on T cells and increased on B cells as a late activation antigen. Product Details