Description

GenieFluor Red 780 Anti-Human CD20 Antibody [BCA/B20]

The GenieFluor Red 780 Anti-Human CD20 Antibody (BCA-B20) offered by AssayGenie is a cutting-edge tool for researchers studying CD20, a cell surface marker commonly found on B cells. This monoclonal antibody is meticulously designed for highly specific binding to human CD20 molecules, enabling precise detection and analysis in various experimental settings. With its superior reactivity and validated performance, the GenieFluor Red 780 Anti-Human CD20 Antibody (BCA-B20) is ideally suited for use in techniques like flow cytometry, immunofluorescence, and immunohistochemistry. Its exceptional sensitivity and specificity make it an invaluable asset for investigations in immunology, oncology, and related fields.

CD20 is a well-known target for therapies in diseases such as lymphomas, leukemias, and autoimmune disorders. Research on CD20 expression and function is essential for developing innovative treatments and understanding the mechanisms underlying these conditions. The GenieFluor Red 780 Anti-Human CD20 Antibody (BCA-B20) offers reliable support for scientists striving to unravel the complexities of CD20 biology and advance medical knowledge for improved patient care.

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Product Title:	GenieFluor Red 780 Anti-Human CD20 Antibody [BCA/B20]
SKU:	AGEL3116
Size:	20 Tests, 100 Tests, 200 Tests
Clone No:	BCA/B20
Synonyms:	B-lymphocyte antigen CD20;MS4A1;B-lymphocyte surface antigen B1;Bp35;Leukocyte surface antigen Leu-16;Membrane-spanning 4-domains subfamily A member 1;MS4A1;CD20;
Host Species:	Mouse
Reactivity:	Human
Application:	FCM

Isotype:	Mouse IgG2a, κ
Isotype Control:	Genie Fluor Red 780 Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:	Liquid
Conjugation:	Genie FluorRed 780
Recommended Use:	Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:

Swissprot:	P11836
Gene ID:	931
Storage Buffer:	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:	CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.

GenieFluor Red 780 Anti-Human CD20 Antibody [BCA/B20] (AGEL3116)

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