GenieFluor Red 780 Anti-Human CD11b Antibody [ICRF44]
The GenieFluor Red 780 Anti-Human CD11b Antibody (ICRF44) offered by AssayGenie is a powerful tool for researchers studying the CD11b cell surface marker, which is primarily expressed on human macrophages, dendritic cells, and granulocytes. This antibody has been specifically designed for use in flow cytometry applications, allowing for precise identification and characterization of CD11b-positive cells in various biological samples.The GenieFluor Red 780 Anti-Human CD11b Antibody (ICRF44) demonstrates high affinity and specificity for the CD11b protein, providing researchers with reliable and reproducible results in their experiments.
By targeting CD11b, this antibody enables detailed analysis of immune cell populations and their involvement in inflammatory responses, immune regulation, and host defense mechanisms.With its exceptional performance and versatility, the GenieFluor Red 780 Anti-Human CD11b Antibody (ICRF44) is an invaluable tool for studies related to immunology, inflammation, infectious diseases, and cancer research. Researchers can rely on this antibody to enhance their understanding of CD11b-expressing cells and their role in physiological and pathological processes, ultimately contributing to advancements in the field of biomedical research.
Product Title:
GenieFluor Red 780 Anti-Human CD11b Antibody [ICRF44]
SKU:
AGEL2997
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
ICRF44
Synonyms:
Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
Genie Fluor Red 780 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
Genie FluorRed 780
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P11215
Gene ID:
3684
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αMintegrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2(CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.