The GenieFluor 647 Anti-Mouse Perforin Antibody (S16009A-AGEL3312) is a cutting-edge tool designed for researchers working in the field of immunology. This antibody is specifically tailored to recognize and bind to mouse perforin, a key protein involved in immune response.Perforin, a pore-forming protein found in cytotoxic T cells and natural killer cells, plays a crucial role in the immune system's ability to eliminate infected or abnormal cells. By targeting perforin, researchers can gain valuable insights into how the immune system functions and how it can be harnessed to combat diseases such as cancer and viral infections.The GenieFluor 647 Anti-Mouse Perforin Antibody offers high sensitivity and specificity, making it a reliable tool for various experimental applications, including immunofluorescence and flow cytometry.
Its versatility allows for the precise visualization and quantification of perforin in different cell types and tissues, providing researchers with valuable data to advance their understanding of immune responses.Whether investigating the mechanisms of immune surveillance, studying the pathogenesis of infectious diseases, or exploring novel immunotherapeutic strategies, the GenieFluor 647 Anti-Mouse Perforin Antibody is an essential resource for researchers seeking to unravel the complexities of the immune system.
Genie Fluor 647 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Genie Fluor647
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P10820
Gene ID:
18646Â
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
Perforin is a 70 kD cytolytic protein that is expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. Perforin is one of the major effector molecules used by cytotoxic T cells and NK cells to mediate targeted cell lysis.