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GenieFluor 647 Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5] (AGEL2227)

SKU:
AGEL2227
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2b, κ
Clone:
RB6-8C5
Conjugation:
AF647
€119
Frequently bought together:

Description

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GenieFluor 647 Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5]

The GenieFluor 647 Anti-Mouse Ly-6G/Ly-6C (GR-1) Antibody (RB6-8C5) from Assay Genie is a crucial tool for researchers studying the immune system in mouse models. This antibody targets the Ly-6G/Ly-6C protein complex, also known as GR-1, which is expressed on the surface of myeloid cells, particularly granulocytes and monocytes. By specifically binding to this protein complex, the RB6-8C5 antibody allows for accurate detection and analysis of these cell populations in various experimental settings.The Ly-6G/Ly-6C (GR-1) antibody is essential for investigating the roles of myeloid cells in immune responses, inflammation, and cancer progression in preclinical studies.

Its high specificity and reactivity with mouse samples make it a valuable tool for researchers seeking to understand the functions and dynamics of these cell populations in different disease contexts. With its validated performance in applications such as flow cytometry and immunofluorescence, this antibody enables precise identification and characterization of Ly-6G/Ly-6C-expressing cells, providing insights into their roles in immune regulation and pathology.

Product Title:GenieFluor 647 Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5]
SKU:AGEL2227
Size:50 Tests, 100 Tests, 200 Tests
Clone No:RB6-8C5
Synonyms:Gr-1;Gr1;Ly-6G/Ly-6C;Ly6G/Ly6C;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor 647 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P35461 P0CW03
Gene ID:546644 ,17067
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.

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