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GenieFluor 647 Anti-Mouse CD8a Antibody [53-6.7] (AGEL2206)

SKU:
AGEL2206
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, κ
Clone:
53-6.7
Conjugation:
AF647
€109 - €249
Frequently bought together:

Description

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GenieFluor 647 Anti-Mouse CD8a Antibody [53-6.7]

The GenieFluor 647 Anti-Mouse CD8a Antibody (53-6.7) is a cutting-edge tool designed for research involving the CD8a cell surface molecule in mice. This antibody, specifically designed for mouse samples, is raised using advanced techniques to ensure high reactivity and specificity. Validated for use in a variety of applications, including immunofluorescence and flow cytometry, it enables precise detection and analysis of CD8a protein expression in different cell types.CD8a is a crucial component of the immune system, playing a central role in the identification and elimination of infected or abnormal cells. Its involvement in immune response regulation makes it a key target for studies in immunology, infectious diseases, and cancer research.

By gaining insights into the function and expression of CD8a, researchers can uncover new therapeutic strategies for enhancing immune responses or targeting malignant cells.With its exceptional sensitivity and reliability, the GenieFluor 647 Anti-Mouse CD8a Antibody (53-6.7) offers a valuable tool for researchers seeking to delve deeper into the complexities of immune cell function and differentiation in mice. Whether investigating T cell biology, studying immune responses to pathogens, or exploring immune-mediated diseases, this antibody provides essential support for cutting-edge research endeavors.

Product Title:GenieFluor 647 Anti-Mouse CD8a Antibody [53-6.7]
SKU:AGEL2206
Size:50 Tests, 100 Tests, 200 Tests
Clone No:53-6.7
Synonyms:T-cell surface glycoprotein CD8 alpha chain;CD8A;T-lymphocyte differentiation antigen T8/Leu-2;MAL;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor 647 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P01731
Gene ID:12525
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.

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