The GenieFluor 647 Anti-Mouse CD73 Antibody (TY-23) is a highly specific and reliable tool for researchers studying CD73, a cell surface enzyme known for its role in immune regulation and inflammation modulation. This antibody, developed by Assay Genie, is specially designed for detecting CD73 in mouse samples and is validated for various applications including immunofluorescence and flow cytometry.CD73, also known as ecto-5'-nucleotidase, plays a critical role in the conversion of extracellular adenosine monophosphate (AMP) to adenosine, thereby influencing immune responses and inflammation pathways.
Understanding the expression and activity of CD73 is essential in research related to immunology, cancer biology, and inflammatory diseases. The GenieFluor 647 Anti-Mouse CD73 Antibody (TY-23) provides researchers with a powerful tool to visualize and analyze CD73 expression in different cell types, enabling detailed investigations into its functions and potential therapeutic applications.
Genie Fluor 647 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Genie Fluor647
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
Q61503
Gene ID:
23959
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD73 (ecto-5`-nucleotidase) is a 69 kD GPI-anchored surface protein. In mice, expression of CD73 in bone marrow is restricted to CD11b+ myeloid cells. In spleen, it is largely expressed on T cells.