The GenieFluor 647 Anti-Mouse CD45.2 Antibody (104-2) from Assay Genie is a highly specialized tool for researchers studying mouse immune cell populations. This monoclonal antibody is specifically designed to target CD45.2, a key cell surface marker involved in immune cell identification and classification.With its fluorescent GenieFluor 647 conjugation, this antibody allows for precise visualization and analysis of mouse CD45.2-positive cells in flow cytometry, immunofluorescence, and microscopy applications. The high specificity and sensitivity of this antibody ensure reliable and accurate results, making it an essential component for immunology and cell biology research.
By targeting CD45.2, researchers can gain insights into immune cell subpopulations, cell signaling pathways, and immune responses in various experimental models. This antibody's versatility and reliability make it an indispensable tool for investigating immune function, inflammation, and immune-related diseases in mouse models.For researchers seeking a robust and validated tool for mouse CD45.2 detection, the GenieFluor 647 Anti-Mouse CD45.2 Antibody (104-2) is a top choice, offering precision, accuracy, and reproducibility for a wide range of research applications.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Gene ID:
19264
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD45.2 is an alloantigen of CD45, expressed by Ly5.2 bearing mouse strains (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in the mouse that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.